Tag Archives: viral infection

Pepto Bismol and Children

The Pink Stuff – Harmless or Deadly…

Bismuth Sub-salicylate is a drug used to treat temporary discomforts of the stomach and gastrointestinal tract such as diarrhea, indigestion, heartburn and nausea. Commonly known as pink bismuth, it is the active ingredient in medications such as Pepto-Bismol and Kaopectate.

Bismuth subsalicylate is in a class of medications called antidiarrheal agents. It works by decreasing the flow of fluids and electrolytes into the bowel, reduces inflammation within the intestine, and may kill the organisms that can cause diarrhea.

But, in the gastrointestinal tract, Bismuth Sub-salicylate is converted to salicylic acid (aspirin) and insoluble bismuth harmless_or_deadly_find_outsalts.

There are adverse effects with this drug, most prominently; Reye’s Syndrome. It can also cause a black tongue and black stools in some users of the drug, when it combines with trace amounts of sulfur in saliva and the colon to form bismuth sulfide. Bismuth sulfide is a highly insoluble black salt, and the discoloration seen is temporary and and supposedly harmless.

Children should not take medication with bismuth subsalicylate because epidemiologic evidence points to an association between the use of salicylate-containing medications during viral infections and the onset of Reye’s Syndrome.

Never give a child under the age of 19 any product with aspirin when suffering from flu symptoms or a viral infection, including products like Pepto-Bismol or Kaopectate!

For the same reason, it is recommended that nursing mothers not use medication containing bismuth subsalicylate like Pepto-Bismol because small amounts of the medication are excreted in breast milk and pose a risk of triggering Reye’s Syndrome to nursing children.

pepto_burnedBismuth subsalicylate is the only active ingredient in an over the counter Drug that can leave a shiny metal oxide slag behind after being completely burnt with a blow torch.

 

 

 

Before you, as an adult, take bismuth subsalicylate:
— tell your doctor or pharmacist if you are allergic to salicylate pain relievers such as aspirin, choline magnesium trisalicylate, choline salicylate (Arthropan), diflunisal (Dolobid), magnesium salicylate (Doan’s, others), and salsalate (Argesic, Disalcid, Salgesic); or any other medication.

— tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to talk to your doctor or pharmacist about taking bismuth subsalicylate if you take: anticoagulants (‘blood thinners’) such as warfarin (Coumadin); a daily aspirin; or medication for diabetes, arthritis or gout.

— if you are taking tetracycline antibiotics such as demeclocycline (Declomycin), doxycycline (Doryx, Vibramycin), minocycline (Dynacin, Minocin), and tetracycline (Sumycin), take them at least 1 hour before or 3 hours after taking bismuth subsalicylate.

— ask your doctor before taking this medication if you have ever had an ulcer, bleeding problem, stools that are bloody or blackened, or kidney disease. Also ask your doctor before taking bismuth subsalicylate if you have a fever or mucus in your stool.

We never recommend giving bismuth subsalicylate to a child or teenager, but if you do, be sure to tell the child’s doctor if the child has any of the following symptoms before he or she receives the medication: vomiting, listlessness, drowsiness, confusion, aggression, seizures, yellowing of the skin or eyes, weakness, or flu-like symptoms. Also tell the child’s doctor if the child has not been drinking normally, has had excessive vomiting or diarrhea, or appears dehydrated.

— ask your doctor about taking this medication if you are pregnant or are breast-feeding.pepto_not_for_kids

Brand Names:
Bismusal®
Kaopectate®
Peptic Relief®
Pepto-Bismol®
Pink Bismuth®
Stomach Relief®

You can get a complete list of medications containing bismuth subsalicylate by clicking this link

Please think twice, and read the label warnings, before giving a child under the age of 19 any drugs that contain aspirin, salicylates, or bismuth-subsalicylate! You can get a list of ‘other names for aspirin’ here.

And always remember: Kids and Aspirin Products DON’T Mix!

Related Information:

Like this information?

donate_baby_angel

Click to Donate and Educate

Advertisements

Comments Off on Pepto Bismol and Children

Filed under Pepto Bismol and Children

Reporting Adverse Medical Effects

Reporting Adverse Reactions To Your Child’s Medications

Most pediatric clinical trials involve a relatively small number of patients, and problems might not be detected until the reporting_saves_lives products are in widespread use. And a drug or device might be studied in one pediatric age group, but prescribed and used in another age group in which it has not been studied, the FDA states.

Consumers can play a critical role in helping the Food and Drug Administration (FDA) assure children’s access to safe medical products.

Reporting to FDA such “adverse events” as unexpected, serious side effects, accidental exposure, and product quality issues can prompt the agency to act—and it can also bring new pediatric safety information to light.

In 2012, FDA received nearly 900,000 adverse event and medication error reports, but only 5 percent were associated with children under 18 years of age. Either parents or caregivers don’t know that they can report adverse effects to the FDA, or they don’t know how.

In 2007, the agency began receiving consumer accounts of serious side effects in children who were accidentally exposed to prescription topical testosterone gel products through contact with the skin of an adult male in their household who was using these products.

This information triggered an FDA investigation that resulted in stronger warning labels to alert the public. FDA also worked with testosterone gel product manufacturers to create potentially safer versions and to identify places on the body where the gel could be applied so that it is less likely to come into contact with children.

These reports from consumers made a big difference. the FDA found it extremely rewarding to work with those families who suspected that something might be going wrong and contacted FDA to investigate the situation. The FDA wants to prevent these harmful situations from happening to others and ensure medical products are safe for everyone to use.

What to Include:

Many adverse event reports do not include relevant information, such as the patient’s age, which can delay the identification of serious problems in children.

“The quality of reports is important,” says OSE director Gerald Dal Pan, M.D., M.H.S. “Document what is happening as much as possible. FDA needs the same kind of information as your health care provider to assess a potential problem with a medication.”

Consumers don’t have to prove that a medication or device caused the problem. “What I have found to be most helpful in reports from consumers is a clear statement about the event, followed by a more detailed description of what happened,” says Wyeth. FDA also recommends including information about:

  • Product name, type, dose, and how it was given (or administered);
  • How long the product was used;
  • Age of the child;
  • Other medications or medical conditions present at the time of event;
  • Outcome (such as what happened to the child if the medical product was stopped); and
  • Contact information for the person submitting the report and for the child’s health care professional.

Consumers often have the most details about what they are experiencing and should contact their health care provider for medical care, and then report the problem to the FDA.

What Happens to the Report

Each report is stored in a database monitored by FDA staff, who evaluate the reports, consult with medical staff and the manufacturer, and determine if more study is needed. There is a wide range of ways for FDA to communicate new safety information to the public, including warnings in the product label, patient monitoring recommendations, dosage adjustments for certain patients, medication guide updates, special programs like registries, and product withdrawal. (Medication guides are paper handouts given with certain medications by the pharmacist.)

FDA’s Pediatric Advisory Committee, a group of outside experts, meets two to three times a year to review adverse events for products recently labeled for use in children. Reviews for 215 products have been presented to the committee through September 2012. OPT maintains a Safety Reporting Page with information on products that the advisory committee has evaluated.

report_adverse_effects_to_fdaHow to Submit a Report:

Consumers should report serious side effects or product quality problems to FDA’s MedWatch: The FDA Safety Information and Adverse Event Reporting program.

There are three routes available to submit voluntary adverse event reports to the FDA:

You can also choose to print the blank form, fill out by hand, and submit

  • Call FDA at 1-800-FDA-1088 to report by telephone

Report Adverse Vaccine Events at: https://vaers.hhs.gov/esub/step1

Related Information for Consumers:

Report suspected unlawful sale of medical products on the Internet at: http://www.accessdata.fda.gov/scripts/email/oc/buyonline/buyonlineform.cfm

If you need information or if you have questions or comments about a medical product, please call the FDA’s toll-free information line, 1-888-INFO-FDA (1-888-463-6332) Press 2, followed by 1 for information, then:
for dietary supplements, select 2
for drug products, select 3
for medical devices, select 4
for biologics, including human cells, tissues, and cellular and tissue-based products, select 6

You will receive an acknowledgement from FDA when your report is received. Reports are reviewed by FDA staff. You will be personally contacted only if we need additional information.

What is a Serious Adverse Event?
An adverse event is any undesirable experience associated with the use of a medical product in a patient. The event is serious and should be reported to FDA when the patient outcome is:

Death
Report if you suspect that the death was an outcome of the adverse event, and include the date if known.

Life-threatening
Report if suspected that the patient was at substantial risk of dying at the time of the adverse event, or use or continued use of the device or other medical product might have resulted in the death of the patient.

Hospitalization (initial or prolonged)
Report if admission to the hospital or prolongation of hospitalization was a result of the adverse event.

Emergency room visits that do not result in admission to the hospital should be evaluated for one of the other serious outcomes (e.g., life-threatening; required intervention to prevent permanent impairment or damage; other serious medically important event).

Disability or Permanent Damage
Report if the adverse event resulted in a substantial disruption of a person’s ability to conduct normal life functions, i.e., the adverse event resulted in a significant, persistent or permanent change, impairment, damage or disruption in the patient’s body function/structure, physical activities and/or quality of life.

Congenital Anomaly/Birth Defect
Report if you suspect that exposure to a medical product prior to conception or during pregnancy may have resulted in an adverse outcome in the child.

Required Intervention to Prevent Permanent Impairment or Damage (Devices)
Report if you believe that medical or surgical intervention was necessary to preclude permanent impairment of a body function, or prevent permanent damage to a body structure, either situation suspected to be due to the use of a medical product.

Other Serious (Important Medical Events)
Report when the event does not fit the other outcomes, but the event may jeopardize the patient and may require medical or surgical intervention (treatment) to prevent one of the other outcomes. Examples include allergic brochospasm (a serious problem with breathing) requiring treatment in an emergency room, serious blood dyscrasias (blood disorders) or seizures/convulsions that do not result in hospitalization. The development of drug dependence or drug abuse would also be examples of important medical events.

Related Information:

What Is Reye’s Syndrome

After Giving a Child Aspirin

Aspirin Containing Products

Other Names for Aspirin

Fraudulent Flu Products

Herbal Remedies

Kids And OTC Medicines

OTC Medicines Kids Should NOT Take

Multiple Combination Meds and Your Child

Like this information?

donate_baby_angel

Click to Donate and Educate

Comments Off on Reporting Adverse Medical Effects

Filed under Reporting Adverse Medical Effects

Kids and OTC Medicines Kids Should NOT Take!

FDA Statement: “Aside from drugs for fever or pain, most over-the-counter products haven’t actually been studied in children for effectiveness, safety, or dosing.”

In a recent poll conducted by University of Michigan C.S. Mott Children’s Hospital, 40 percent of parents are giving some_drugs_are_not_for_childrenchildren under the age of 4 over the counter cold medicines, even after the FDA issued a warning that OTC medicines should not be used in this age group.  Twenty Five percent of these parents gave their child decongestants!

Manufacturers of OTC cold medicines changed their warning labels in 2008 to reflect the dangers of giving these medicines to young children, Six years of age and under.

One of the problems is that the medicines themselves are still labeled “Children’s” medication, and just like the issue with “Baby” aspirin, parents don’t think to read the label and they assume the product is safe for all children when in fact, it is not.

(Currently, there is no longer a product packaged or marketed as “baby aspirin” because in 2011, the National Reye’s Syndrome Foundation met with the FDA, stressing the danger in using the term “baby” in representing low-dose aspirin. FDA and aspirin manufacturers agreed, and there is no such thing as ‘baby’ aspirin anymore, and children are safer because of this change.)

The side effects from use of cough and cold medicines in young children may include:

  • allergic reactions
  • increased or uneven heart rate
  • drowsiness or sleeplessness
  • slow and shallow breathing
  • confusion or hallucinations
  • convulsions
  • nausea
  • constipation.

“Products like these may work for adults, and parents think it could help their children as well. But what’s good for adults is not always good for children,” says Dr Matthew Davis, Director of the C.S. Mott Children’s Hospital National Poll on Children’s Health.

READ. THE. LABEL.learn_to_read_labels

OTC drugs have information on the bottle or box. Always read this information before using the medicine. This information tells you:

How much to give; Medication doses for infants and young children are based on age and weight. Know your child’s weight.

Follow the directions for age and weight. If the recommended age is not your child’s age, don’t give the medicine.

If no dose is given on the bottle or package for children under 12 years old, ask your doctor or pharmacist if it is OK to give the medicine to your child, how much you should give, and when you should give it.

Liquid medicines usually come with a cup, spoon or syringe to help measure the right dose. Always use these devices to give medicine to infants and very young children. Using a kitchen teaspoon is not an accurate way to measure. A teaspoon is usually considered to be 5 cc or 5 mL, but kitchen teaspoons can vary in size from between 2 mL and 10 mL.

If you want to mix medicine with milk or formula, first put the medicine in one ounce of milk and have the child drink it all. Then feed the remaining formula or milk in the bottle and let them finish however much more they want.

Always measure or give medication with a good light turned on. Insufficient light could cause you to give the wrong medicine or the wrong dose.

Never let young children take medicine by themselves.

How often to give Medicines; Some medicines state every 6 hours, or every 8 hours. Does this mean ‘waking’ hours; hours when the child is awake, or actual hours as around the clock? Ask your Pharmacist this question so you know exactly when to give your child the medicine. Then keep track of the times you give the medicine to your child on a chart tapped to your refridgerator, or the location the medication is stored.

What the drug contains – Be certain you are not double dosing your child!

Many OTC cough and cold medicines contain a combination of ingredients to treat several symptoms. Your child might be getting some of the same ingredients in other medicines. For example, Tylenol and Nyquil contain the same ingredient, acetaminophen. Be sure to read the list of active ingredients (the ingredients that make the medicine work) for each OTC medicine you give your child to make sure he or she is not getting a double dose of the same medication. You need to make sure that the total amount of a medicine does not exceed the recommended dose.

Combinations of medicines found in multi-symptom medicines may cause side effects in children. The combination of antihistamines and decongestants in some “cold remedy” medicines can have side effects such as hyperactivity, sleeplessness and irritability in children. To be safe, don’t combine prescriptions, supplements or multi-symptom medicines without checking with your health care provider or pharmacist.

Watch The Ingredients List:

Sometimes the ingredients for a medicine change but the name stays the same. For example, the formulation of Kaopectate, an OTC medicine for diarrhea, changed so it now contains bismuth subsalicylate. The older versions contained only kaolin and pectin. (Bismuth subsalicylate is also found in Pepto-Bismol, an OTC medicine for upset stomach and diarrhea.) Bismuth subsalicylate is NOT recommended for children younger than 19 because of the risk of the rare but deadly condition; Reye’s Syndrome.

Because of Reye’s syndrome, DO NOT give a child younger than 19 any product with aspirin or similar drugs called “salicylates” unless your doctor tells you to. Instead of aspirin or other salicylates, you can give your child acetaminophen (sold as Tylenol and other brands). There are many names for aspirin (salicylates) and you can see the list here: https://reyessyndrome.wordpress.com/2012/12/30/other-names-for-aspirin/

Be sure to take into consideration the concentrations of ingredients when you determine the amount you give your child. Medicines with the same brand name can be sold in different strengths, including infant, children and adult formulas. Infant drops of some medicines, for example, are stronger than the liquid elixir of the same medicine for toddlers or children. This is because infants may not be able to drink a large volume of medicine to give their proper dosage. Don’t make the mistake of giving higher doses of the infant drops to a toddler thinking the drops are not as strong.

Warnings about using the drug: Always Read the ‘Black Box’ – the warnings box!

If the drug is safe for children of certain ages: If your child’s age is not listed, do not use the product. One exception to age, is the Reye’s Syndrome warning on labels: The National Reye’s Syndrome Foundation collects Case Reports of Reye’s Syndrome and has found that Reye’s predominately attacks children up to the age of 19, whereas the FDA label only states age 12. Don’t use aspirin or aspirin containing products in children under the age of 19.

And if you are not sure – Ask the Pharmacist at the store. They will be happy to help you!

Other Tips:

Talk to your doctor, pharmacist, or nurse to find out what mixes well and what doesn’t. Medicines, vitamins, supplements, foods and beverages don’t always mix well with one another. Select products with the fewest number of ingredients needed to treat your symptoms.

Talk to your Doctor or Pharmacist before giving a child a ‘home remedy’, or homeopathic drug found on the Internet!  Many of these are quite harmful, and have no professional approval to use.  Know what you are giving your child, otherwise, it could be deadly!

Don’t call medications “candy.” If children come upon medications at a later time, they may consider it “candy” and eat it without your knowing.

Always use child-resistant caps and store medicines in a safe place. Relock the cap after each use. Be especially careful with any products that contain iron; they are the leading cause of poisoning deaths in young children. All medications become less effective (expire) over time and should be replaced. Check the expiration date before using any product.

Store medicines in a cool, dry area. The heat from kitchens and the moisture from bathrooms decrease the effectiveness of medications.  Store all medications out of the reach of children.

Before you give a medicine, check the outside packaging for damage such as cuts, slices, or tears; check the label on the download_free_medication_chartinside package to be sure you have the right medicine. Make sure the lid and seal are not broken. Check the color, shape, size and smell of the medicine. If you notice anything different or unusual, talk to a pharmacist or your health care provider.

Use a chart to keep track of dosage dates and times.  A Free Chart can be downloaded by clicking here.

Classes of OTC Medicines

Analgesics treat pain and fever:

Use caution with different forms of these drugs, because some are more concentrated than others. Common analgesics for infants and children are acetaminophen (Tylenol) and ibuprofen (Advil and Motrin).

WARNINGS:

  • DO NOT give aspirin to children younger than 19, because it can cause a rare but deadly disease called Reye’s Syndrome.
  • DO NOT use ibuprofen in children younger than 6 months. Know how much your child weighs before giving ibuprofen.

Antihistamines treat runny noses, itchy eyes and sneezing caused by allergies (but not colds). Some can cause sleepiness. Examples of antihistamines include brompheniramine (often in combination with decongestants such as phenylephrine as in Dimetapp and other medicines); chlorpheniramine (Chlor-Trimeton and other medicines); diphenhydramine (Benadryl and other medicines); cetrizine (Zyrtec); and loratadine (Claritin and other medicines).

WARNINGS:

  • These are not recommended for children younger than 6, because they can even affect learning.
  • Use only with your health care provider’s advice in young infants or children with asthma.

Expectorants and combination cough medications may help loosen mucus. Cough suppressants numb the reflex to cough. Coughing is necessary to clear mucus and debris bacteria from the lungs, so check with your child’s health care provider before using cough-suppressing syrups. Guaifenesin, an expectorant, promotes the production of thin mucus that is more easily removed by coughing.

WARNINGS:

  • These are not recomended for children under the age of 6.

Decongestants can relieve stuffiness caused by allergies or colds by temporarily shrinking the membranes in the nose to make breathing easier. They should not be used for more than two to three consecutive days. Decongestants taken by mouth can have a number of side effects such as irritability, sleeplessness, dizziness. Examples of decongestants include phenylephrine (found in Neo-Synephrine nose drops and other medicines); and pseudoephedrine (Sudafed, PediaCare Infant Decongestant Drops and other medicines).

WARNINGS:

  • These are not recommended for children under the age of 6.

Medicines for diarrhea. These are usually not necessary. Instead, give your child plenty of fluids and let the disease run its course. Diarrhea, however, can be dangerous in newborns and infants. In small children, severe diarrhea lasting just a day or two can lead to dehydration. Because a child can die from dehydration within a few days, you should see a health care provider as soon as possible if an infant has diarrhea. Talk to your provider before giving these medicines to infants or children.

WARNINGS:

  • Diarrhea medicines containing bismuth subsalicylate (Pepto-Bismol, Kaopectate, and other medicines) should NOT be given to a child younger than 19, as these could trigger Reye’s Syndrome, a deadly disease in children.
  • Loperamide (Imodium and other medicines), should NOT be given to a child younger than 6.

Laxatives relieve constipation and work by several methods. Some add fiber or water to stool to make it more bulky and easier for intestines to eliminate it; some coat the surface of the stool to make it more slippery; some soften the stool so it passes more easily; and others cause the intestines to contract more forcefully. Examples of laxatives include glycerin suppositories; magnesium citrate; magnesium hydroxide (Milk of Magnesia and other medicines); mineral oil (Agoral, Kondremul and other medicines); psyllium (Metamucil, Fiberall and other medicines); senna (Senokot, Ex-Lax and other medicines); methylcellulose (Citrucel and others), castor oil, and sodium phosphate (Fleet and other medicines).

WARNINGS:

  • DO NOT give infants or children laxatives without talking to your child’s health care provider.

Summary:
Aside from drugs for fever or pain, most over-the-counter products haven’t actually been studied in children for effectiveness, safety, or dosing.

  • When you give medicine to your child, be sure you’re giving the right medicine and the right amount.
  • Read and follow the label directions.
  • Use the correct dosing device. If the label says two teaspoons and you’re using a dosing cup with ounces only, don’t guess. Get the proper measuring device. Don’t substitute another item, such as a kitchen spoon.
  • Talk to your doctor, pharmacist, or other health care provider before giving two medicines at the same time. That way, you can avoid a possible overdose or an unwanted interaction.
  • Follow age and weight limit recommendations. If the label says don’t give to children under a certain age or weight, don’t do it.

Resources:
National Reye’s Syndrome Foundation, Food and Drug Administration, CDC, National Institutes of Health

Related Information:
What Is Reye’s Syndrome
Aspirin and Reye’s Syndrome
Other Names for Aspirin
Teens & Aspirin
Chicken Pox Parties
Herbal Remedies

Like this information?

donate_baby_angel

Click to Donate and Educate

Comments Off on Kids and OTC Medicines Kids Should NOT Take!

Filed under Kids and OTC Medicines

Antibiotics – Don’t Take This With That!

Antibiotics are medicines that help stop bacterial infections. Protect yourself and your family by taking them correctly. There are times when you should and when you should not take antibiotics.

In children, antibiotics are the most common cause of emergency department visits for adverse drug events. Rest, fluids, and over-the-counter products may be your or your child’s best treatment option.

And NEVER give a child under the age of 19 aspirin or aspirin containing products, as it could trigger Reye’s Syndrome, a deadly disease!

The main types of germs that cause infections:antibiotics_dttwt

Viruses and bacteria are the two main types of germs that cause infection.

Antibiotics cannot kill viruses but can kill bacteria. Viral infections should not be treated with antibiotics.

Viral illnesses include:

  • Common cold – stuffy nose, sore throat, sneezing, cough headache.
  • Influenza (flu) – fever, chills, body aches, headache, sore throat, dry cough.
  • Many coughs.
  • Acute bronchitis (cough, fever) – almost always caused by viruses.
  • Pharyngitis (sore throat) – most sore throats are caused by viruses and are not effectively treated with an antibiotic.
  • Viral gastroenteritis.

Bacterial infections should be treated with antibiotics. Bacterial infections can include:

  • Ear infections – antibiotics are used for most, but not all ear infections.
  • Severe sinus infections – lasting two or more weeks.
  • Strep throat.
  • Urinary tract infection.

Antibiotics can sometimes interact with other medicines or other substances. This means that the effects of one of the medicines can be altered by the other.

Some of the more common interactions are listed below. However, this is not a complete list.

If you want to check that your medicines are safe to take with your antibiotics, ask your GP or local pharmacist. You should also always carefully read the patient information leaflet that comes with your medicine.

Combined oral contraceptives

Antibiotics may cause your combined oral contraceptive pill to be less effective at preventing pregnancy.

Women taking combined oral contraceptives should use an extra method of contraception (for example, condoms) while taking the antibiotics and, in some cases, for seven days after finishing the course. Your GP will be able to advise you.

Medications To Avoid:

Penicillin

It is usually recommended that you avoid taking penicillin at the same time as a medication called methotrexate, which is used to treat some types of cancers and severe autoimmune conditions such as the skin condition psoriasis. This is because combining the two medications can cause a range of unpleasant and sometimes serious side effects.

You may experience a skin rash if you take penicillin and a medication called allopurinol, which is used to treat gout.

Cephalosporins

Cephalosporins may not be suitable to take if you are also taking blood-thinning medications such as heparin and warfarin.

If you need treatment with cephalosporins, you may temporarily have to stop taking the blood-thinning medication.

Aminoglycosides

The risk of damage to your kidneys and hearing is increased if you are taking one or more of the following medications:

  • antifungals – used to treat fungal infections
  • cyclosporin – used to treat autoimmune conditions such as Crohn’s disease and given to people who have had an organ transplant
  • diuretics – used to remove water from the body
  • muscle relaxants

However, the risk of kidney and hearing damage has to be balanced against the benefits of using aminoglycosides to treat life-threatening conditions such as meningitis.

Tetracyclines

You should check with your GP or pharmacist before taking a tetracycline if you are currently taking any of the following medications:

  • vitamin A supplements
  • retinoids such as acitretin, isotretinoin and tretinoin used to treat severe acne
  • blood-thinning medication
  • diuretics
  • kaolin-pectin and bismuth subsalicylate (Pepto Bismol) used to treat diarrhea
  • medicines to treat diabetes such as insulin
  • atovaquone used to treat pneumonia
  • antacids used to treat indigestion and heartburn
  • sucralfate used to treat ulcers
  • lithium used to treat bipolar disorder and severe depression
  • digoxin to treat heart rhythm disorders
  • methotrexate
  • strontium ranelate used to treat osteoporosis
  • colestipol or colestyramine used to treat high cholesterol
  • ergotamine and methysergide used to treat migraines

Macrolides

It is highly recommended that you do not combine a macrolide with any of the following medications (unless directly instructed to by your GP), as the combination could cause heart problems:

  • terfenadine, astemizole and mizolastine – which are all antihistamines used to treat allergic conditions such as hay fever
  • amisulpride – used to treat episodes of psychosis
  • tolterodine – used to treat urinary incontinence
  • simvastatin – used to treat high cholesterol

Fluoroquinolones

You should check with your GP or pharmacist before taking a fluoroquinolone if you are currently taking any of the following medications:

  • theophylline, which is used to treat asthma and also found in some cough and cold medicines
  • the non-steroidal anti-inflammatory drug (NSAID) painkillers such as ibuprofen
  • ciclosporin
  • probenecid used to treat gout
  • clozapine used to treat schizophrenia
  • ropinirole used to treat Parkinson’s disease
  • tizanadine used to treat muscle spasms
  • glibenclamide used to treat diabetes
  • cisapride used to treat indigestion, heartburn, vomiting or nausea
  • tricyclic antidepressants, such as amitriptyline, steroid medications (corticosteroids)

Some fluoroquinolones can intensify the effects of caffeine (a stimulant found in coffee, tea and cola), which could make you feel irritable, restless and cause problems falling asleep (insomnia).

Finally, you may need to avoid taking medication that contains high levels of minerals or iron as this can block the beneficial effects of fluoroquinolones. This includes:

  • antacids
  • zinc supplements
  • some types of multivitamin supplements

Antibiotics that can cause Sun Sensitivity include:  Doxycycline, tetracycline, ciprofloxacin, ofloxacin, levofloxacin, trimethoprim. In some people, the sensitivity can last long after the antibiotic regimine is complete.

Phototoxicity. This is the most common type of sun-sensitivity drug reaction. It can occur when skin is exposed to the sun after certain medications are injected, taken orally, or applied to the skin. The drug absorbs the UV light, then releases it into the skin, causing cell death. Within a few days, symptoms appear on the exposed areas of the body. In some people, symptoms can persist up to 20 years after the medication is stopped. Among the most common phototoxic drugs are the tetracycline family, NSAIDs (nonsteroidal anti-inflammatory drugs such as ibuprofen), and amiodarone (Cordarone, a heart medication).

It’s important to note that not every person who uses these drugs has a reaction. If it does happen, it can be a one-time occurrence, or it can happen each time the drug is taken and sun exposure occurs. People with HIV are among the most likely group to experience sun sensitivity to drugs.

Can I drink alcohol when on an antibiotic?

Alcohol is a drug and in combination with other drugs including antibiotics, can cause an interaction with undesirable results. Ask your doctor about your specific medication, but in general, you should avoid combining alcohol with any medication.

A list of ingredients to avoid, (other names for aspirin) can be downloaded here, or you can email the NRSF for a wallet size card(s) you can carry with you when shopping for medications.

Like this information?

donate_baby_angel

Click to Donate and Educate

Leave a comment

Filed under Don't Take This With That:, Healthy, Wealthy, and Wise....

Multiple Combination Medicines and Your Child

Know Active Ingredients in Children’s Meds

childrensdrugs

If your child is sneezing up a storm, it must be allergy season once more.

And if your child is taking more than one medication at the same time, there could be dangerous health consequences if those medicines have the same active ingredient, according to Hari Cheryl Sachs, M.D., a pediatrician at the Food and Drug Administration (FDA).

A medicine is made of many components. Some are “inactive” and only help it to taste better or dissolve faster, while others are active. An active ingredient in a medicine is the component that makes it pharmaceutically active—it makes the medicine effective against the illness or condition it is treating.

Active ingredients are listed first on a medicine’s Drug Facts label for over-the-counter (OTC) products. For prescription medicines, they are listed in a patient package insert or consumer information sheet provided by the pharmacist.

Many medicines have just one active ingredient. But combination medicines, such as those for allergy, cough, or fever and congestion, may have more than one.

Take antihistamines taken for allergies. “Too much antihistamine can cause sedation and—paradoxically—agitation. In rare cases, it can cause breathing problems, including decreased oxygen or increased carbon dioxide in the blood, Sachs says.

“We’re just starting allergy season,” says Sachs. “Many parents may be giving their children at least one product with an antihistamine in it.” Over-the-counter (OTC) antihistamines (with brand name examples) include diphenhydramine (Benadryl), chlorpheniramine (Chlor-Trimeton), clemastine (Tavist), fexofenadine (Allegra), loratadine (Claritin, Alavert), and cetirizine (Zyrtec).

multiple_combination_medicinesBut parents may also be treating their children for a separate ailment, such as a cough or cold. What they need to realize is that more than one combination medicine may be one too many.

“It’s important not to inadvertently give your child a double dose,” Sachs says.

Other Health Complications

The same goes for other active ingredients, often found in combination products for allergies but also used to treat other symptoms, such as fever, headache or nasal congestion:

  • Acetaminophen (in Tylenol and many other products), a pain reliever often used to treat fevers, mild pain or headache. Taking too much can cause liver damage.
  • Ibuprofen (for example, Advil or Motrin), another common medicine for relieving mild to moderate pain from headaches, sinus pressure, muscle aches and flu, as well as to reduce fever. Too much ibuprofen can cause nausea, vomiting, diarrhea, severe stomach pain, even kidney failure.
  • Decongestants such as pseudoephedrine or phenylephrine (found in brand name drugs such as Actifed and Sudafed) taken in large amounts can cause excessive drowsiness in children. They can also cause heart rhythm disturbances, especially if combined with products and foods containing caffeine. In the form of nasal sprays and nose drops, these products, as well as oxymetazoline (the active ingredients in products such as Afrin), can cause “rebound” congestion, in which the nose remains stuffy or gets even worse.

Never give a child aspirin or aspirin containing products, as you risk triggering Reye’s Syndrome, a deadly disease!

Any of the above symptoms may indicate a need for immediate medical attention. “The bottom line is that neither you, nor your children, should take multiple combination medicines at the same time without checking the active ingredients and consulting your health care professional first,” recommends Sachs.

Furthermore, two different active ingredients may serve the same purpose, Sachs says. For example, both acetaminophen and ibuprofen help reduce pain and fever. So there’s generally no need to give your child both medicines for the same symptoms.

Write It All Down

Whether you’re treating your child’s condition with OTC medicines from the drug store or ones prescribed by your doctor, it’s essential that you keep track of every medicine and the active ingredients each contains, Sachs says.

“It’s easy to forget which medicines you’re giving your child,” Sachs says. “And if you have more than one child, it can get even more complicated.” She recommends making it a habit to write down the name of any medicine you give your child, whether it’s OTC or prescription (download a daily medicine records template).

“It’s really a good idea to carry that list with you when you go to see your pediatrician or even when you go to the pharmacy,” she adds. You should also note whatever vitamins or supplements your child is taking, as these can interact unfavorably with certain medicines, too.

Most importantly, Sachs says parents should always read the Drug Facts label on OTC products, and the patient package insert or consumer information sheet that comes with prescription medicines, every time they’re considering a medication for their child, even if they think they already know the ingredients. They should know that the ingredients can change without an obvious change in the packaging. And they should contact their health care professional with any questions.

A list of ingredients to avoid, (other names for aspirin) can be downloaded here, or you can email the NRSF for a wallet size card(s) you can carry with you when shopping for medications.

Like this information?

donate_baby_angel

Click to Donate and Educate

Leave a comment

Filed under Don't Take This With That:, Healthy, Wealthy, and Wise....

Grapefruit, Drug Interactions

Don’t take this with that! Seriesgrapefruit

Grapefruit causes problems when taken with certain medications

Sometimes the juice just isn’t worth the squeeze…especially when combining grapefruit with medicines.

While it can be part of a balanced and nutritious diet, grapefruit can have serious consequences when taken with certain medications. Currently, there are more than fifty prescription and over-the-counter drugs known to the U.S. Food and Drug Administration that can have negative interactions with grapefruit.

As little as one cup of juice or two grapefruit wedges can alter the way your medicines work. When taken with medicine, grapefruit can delay, decrease, or enhance absorption of certain drugs; as a result, the patient does not receive the prescribed dosage of the medication. If the label on your medicine reads “DO NOT TAKE WITH GRAPEFRUIT” or has similar words, heed the warning. It can save you a bushel of problems.

How it does or doesn’t work

pills

Depending on the active ingredient, grapefruit can reduce the effectiveness of a drug or worse, create potentially dangerous drug levels in the body. Grapefruit can interfere with transporters in the intestine that help absorb drugs. When this happens, less of the drug reaches the bloodstream and the patient receives no benefit.

Grapefruit can also interfere with enzymes that break down drugs in your digestive system. This can result in the body absorbing too much of the drug, which can potentially cause serious problems.

Help may be on the way

Scientists are currently working on breeding hybrid grapefruits that will be safe to mix with medications. In the near future you may be able to enjoy these tasty mounds without compromising your safety. But until the new fruit containers start to arrive, follow these tips:

  • Ask your pharmacist or other health care professional if you can have fresh grapefruit or grapefruit juice while using your medication. If you can’t, you may want to ask if you can have other juices with the medicine.
  • Read the Medication Guide or patient information sheet that comes with your prescription medicine to see if it interacts with grapefruit juice. Some information may advise not to take the drug with grapefruit juice. If it’s OK to have grapefruit juice, there will be no mention of it in the guide or information sheet.
  • Read the Drug Facts label on your non-prescription medicine, which will let you know if you can have grapefruit or other fruit juices with it.
  • If you can’t have grapefruit juice with your medicine, check the label of bottles of fruit juice or drinks flavored with fruit juice to make sure they don’t contain grapefruit juice.
  • Seville oranges (often used to make orange marmalade) and tangelos (a cross between tangerines and grapefruit) affect the same enzyme as grapefruit juice, so avoid these fruits as well if your medicine interacts with grapefruit juice.

Like this information?

donate_baby_angel

Click to Donate and Educate

 

Leave a comment

Filed under Don't Take This With That:, Healthy, Wealthy, and Wise....

Triclosan And Your Child’s Well-being

A hand sanitizer, or antiseptic,  is often used as an alternative to hand washing when soap and water is not readily available. But not all hand sanitizers are created equal, and some may even cause health issues in children and adults.

Practicing good hand hygiene is especially important:wash_hands

After using the bathroom
Before eating or drinking anything
Before and after handling raw foods, fish, poultry, or eggs
After using a public phone
After riding public transportation
In schools and day care centers
After changing diapers
When one is sick
After shaking hands
After sneezing or coughing
After touching an ATM, elevator buttons or escalator handrails

Manufactures claim that sanitizers kill 99.9 percent of germs. But some studies suggest that keeping environments too clean and the persistent use of antibacterial soaps and hand sanitizers may inhibit proper immune system development in children. This is because inflammatory systems require the exposure to common germs to properly develop.

Although the FDA recommends, that when possible, it is better to use soap and water and scrub for at least 20 seconds, that is not always possible in the real world.

So what about hand sanitizers, and can they be dangerous?

There are new studies just out that are claiming that one ingredient used by some manufactures can indeed cause health issues. The ingredient is Triclosan.

Triclosan was first registered as a pesticide in 1969.

Triclosan is an antimicrobial active ingredient contained in a variety of products where it acts to slow or stop the growth of bacteria, fungi, and mildew. It is used in items such as conveyor belts, fire hoses, dye bath vats, or ice-making equipment as an antimicrobial pesticide.

brushteeth2Triclosan is also used in products such as, fabrics, vinyl, plastics (toys, toothbrushes), adhesives, polyethylene, polyurethane, polypropylene, floor wax emulsions, textiles (footwear, clothing), caulking compounds, sealants, rubber, carpeting, and a wide variety of other products.

Triclosan has been used since 1972, and it is present in soaps (0.10-1.00%), deodorants, toothpastes, mouth washes, and cleaning supplies, and is infused in an increasing number of consumer products such as kitchen utensils, toys, bedding, socks, and trash bags.bathing

So your morning routine may start with bathing or showering with soap, brushing your teeth with toothpaste and using mouth wash, perhaps applying some cosmetics, and a dash of deodorant. Then throughout the day, to protect yourself from germs, you use a pocket hand sanitizer, or spray.

Have you checked those items for Triclosan? If the product contains Triclosan, it must be labled.

ingredient_tricolsanSeveral scientific studies have come out since the last time the FDA reviewed Triclosan that warrant further review. According to one recent study, Triclosan may impact respiratory health, by promoting the development of allergies and causing inflammation in the mucous lining of the nose, also known as rhinitis.

Researchers from NIEHS, Norway, and the CDC found the link after measuring levels of Triclosan in urine samples from Norwegian children. The authors published their paper online Nov. 12 in the journal Allergy, and state their findings replicate those of another study that used American children participating in the National Health and Nutrition Examination Survey. Since these reports found an association between Triclosan and the occurrence of allergic sensitization in two different populations, the researchers feel confident the relationship is genuine.

The 623 Norwegian children used in the study have been followed since birth. At age 10, the youngsters received two days of extensive clinical evaluation at Oslo University Hospital, undergoing allergy skin prick tests and lung function assessments on a treadmill, and provided urine and blood samples. The research team sent the urine samples to the Centers for Disease Control and Prevention to measure the amounts of Triclosan.

The results showed that children with allergy sensitivity and rhinitis had the highest levels of Triclosan in their urine. Since Triclosan doesn’t stay in the body very long, 1-2 days according to the study, they think the elevated levels come from continued use of certain products.

Animal studies have shown that Triclosan alters hormone regulation. Other studies in bacteria have raised the possibility that triclosan contributes to making bacteria resistant to antibiotics.

The authors of the study plan to continue examining the Triclosan-allergy connection. They say other research groups have measured Triclosan in breast milk from Swedish mothers and, since Norwegian mothers tend to breastfeed their babies during the first 4-6 months of life, the study plans to follow up the Swedish findings with a study of Triclosan andbreastfeeding allergy development in Norwegian infants. The research team has already collected urine from the newborns and will follow up as they age.

The FDA has partnered with other Federal Agencies to study the effects of Triclosan on animal and environmental health.

So what to do?

Check the labels for Triclosan on the items you and your children use.

Many hand sanitizers, like the PURELL® brand, do not contain Triclosan. Using alcohol based instant hand sanitizers, when soap and water are not available, is one of the Centers for Disease Control and Prevention’s recommendations.

The Centers for Disease Control and Prevention have recommended the use of alcohol-based hand sanitizers when soap and water are not available and hands are not visibly dirty. The CDC recommends that children in school may use alcohol-based hand rubs as an alternative to handwashing.

The main active ingredient in Purell hand sanitizers is ethyl alcohol, the primary germ-killing agent in most hand-sanitizing agents.

According to the Purell company, one of the major benefits of using ethyl alcohol over other germ killing agents is that bacteria have been unable to create a resistance to ethyl alcohol. That means that regardless of how often you use the handsanitizer_purellproduct, the bacteria continue to die.

Other Ingredients Include:

Isopropyl alcohol is also a germ-killing agent. Although the percentage of isopropyl alcohol is much less than ethyl alcohol, both work together to keep your hands free of the bacteria and viruses that cause infection and disease.

Carbomer is a common ingredient used to make gel-like solutions. The carbomer is added to water in Purell by sifting it in. As the carbomer combines with the water, it creates a non-foaming gel.

Tocopheryl acetate is a form of the fat-soluble vitamin E. It is commonly used in skin products as an antioxidant and moisturizer. Its moisturizing properties can help offset the drying effect that ethyl alcohol can cause to the skin.

Glycerin is another common ingredient in skin products. It works in two ways–as a skin moisturizer that absorbs moisture from the air, and to make Purell easier to spread on the skin.

Propylene glycol is a moisturizer that works similar to glycerin. This ingredient pulls moisture from the air and deposits it into the upper layers of the skin, helping to keep skin from drying out.

Isopropyl myrisate works to thicken the consistency of the Purell gel. It also acts as an emollient to prevent the product from feeling oily.

Purell states that aboratory testing has never shown alcohol-based hand sanitizers like PURELL® to lead to bacterial resistance. “There is no evidence that organisms adapt and become immune to the active ingredient in PURELL® products. Once your hands are rubbed dry after application of PURELL®, the alcohol has evaporated completely. PURELL® leaves no harmful residue. A small bit of emollient (skin conditioning agent) is left on the hands after use to leave your hands feeling soft and refreshed.”

Non-alcohol, or some labeled ‘natural’ sanitizers are not as good. Alcohol-based sanitizers work because alcohol breaks up bacterial proteins and kills them.

In the end, know your ingredients, read labels, and choose wisely.

For those interested in trying Purell, here is a link to a coupon: http://www.purell.com/about-us/purell-coupons-promotions.aspx

Citations:
http://www.epa.gov/oppsrrd1/REDs/factsheets/triclosan_fs.htm;

http://www.epa.gov/endo/

Bertelsen RJ, Longnecker MP, Lovik M, Calafat AM, Carlsen KH, London SJ, Lodrup Carlsen KC. 2012. Triclosan exposure and allergic sensitization in Norwegian children. Allergy; doi:10.1111/all.12058 [Online 12 November 2012]

http://www.niehs.nih.gov/news/newsletter/2012/12/science-allergies/

http://www.livestrong.com/article/68666-purell-hand-sanitizer-ingredients/#ixzz2Ms7zvFfg

Leave a comment

Filed under Keeping Kids Healthy